陈一文：邪商恶官用啥加剧帕金森病老年痴呆症抑郁症自闭症灾难？

　　陈一文：邪商恶官用啥加剧帕金森病老年痴呆症抑郁症自闭症灾难?

　　(2015-09-15 13:53:31)育儿 婴儿配方乳粉 正己烷 苯 草甘膦

　　分类： 批判转基因技术

　　1)帕金森病：中国“发病率近20年增长20倍”，目前总共大约170万患者;而且显示年轻化趋势，“青少年型帕金森病”患者占据总人数的10%。2)老年痴呆症(又称阿尔茨海默病)：成老年人第四大杀手，患者总数约有600万，居世界首位，正以每20年翻一番的速度递增，目前老年痴呆患者平均年龄55岁左右，比20年前提前10年，呈现明显的年轻化趋势。3)抑郁症：目前我国抑郁症发病率高达5%～6%,平均发病年龄已低至30岁左右。另据一项流行病学调查估算，中国抑郁焦虑患者已达9000万人，但接受相关药物治疗的患者只占不到10%。我国自杀和自杀未遂的人群中，抑郁症患者占50-70%。4)中国自闭症(也称孤独症)发病率不断攀升，患者已超1000万，发病率约为1%;孤独症儿童发病率20年内升高了10倍, 0到14岁的儿童患病者达200余万。国际上，该病男女的发病率男女比例大约4:1。在我国，男女患病率的比例更为悬殊，约为6:1到9:1之间。

　　1)Parkinson disease: In China, incidence increased 20 times during recent 20 years, according to epidemiological estimations, there are about 1.7 million Parkinson patients in China, shows a trend of becoming younger. "Youth and teenage type Parkinson disease" patients account to 10% of total number of Parkinson disease patients. 2) Alzheimer""""s disease, has become the No.4 killer to old age in China, the number of patients is about 6 million, ranking 1st position in the world, and increase at a rate of doubling every 20 years; The average age of Alzheimer""""s disease at present is about 55 years old in China, 10 years younger than the average age of patients 20 years ago; 3) Depression: The preva1ence rate of depression in China is already 5% - 6%, average age advanced to about 30 years. According to estimations by another epidemiology survey, China at present has about 90 million depression patients, Among suicide and suicide attempts, depression patients account to 50% - 70%. 4) China""""s autism incidence is continue rising, exceeding 10 million patients at present, incidence rate about 1%; China""""s children autism incidence has increased 10 times over the past 20 years，with over 2 million 0 - 14 years old children patients. International, the ratio of male/female autism patients is about 4:1. In China, this ratio is about 6:1 to 9:1.

　　邪商恶官勾用啥加剧帕金森病、老年痴呆症、抑郁症、自闭症灾难?

　　What have greedy companies and evil officers used to worsen the disaster of Parkinson, Alzheimer""""s, Depression and Autism disease in China!?

　　许多帕金森病、老年痴呆症、抑郁症、自闭症患者，当然各自有各自的病因与症候。但是，将中国近二十年发生率剧增的帕金森病、老年痴呆症、抑郁症、自闭症进行整体流行病学研究与综合分析，就能发现它们在病因、年龄趋势特征、分布等等方面，是具有显著共性特征的一组疾病：

　　Many Parkinson, Alzheimer""""s, Depression and Autism disease patients surely have their individual causes. But, if overall comprehensive epidemiological studies and analysis is carried out Parkinson, Alzheimer""""s, Depression and Autism disease rapidly increasing during the past 20 years, then from their causes, age trend, distribution etc., can discover they are a group of diseases with significant commonalities.

　　1)由于慢性或进行性大脑结构的器质性损害引起的高级大脑功能障碍的一组疾病与症候群;

　　1) A group of syndrome of advanced brain dysfunction caused by chronic or progressive brain structure physical damage;

　　2)平民大众，特别幼童、小学生、中学生与大学生，持续普遍食用一系列食品含微量毒性农药(除草剂、杀虫剂等)、化学品(神经毒素正己烷、苯及其衍生物、石油残渣“不挥发物”等)、生化物质(Bt毒素等)残留，对他们的大脑器质性损伤病变;

　　2) A series of food continue and popular consumed by ordinary people, especially young children, primary school, middle school and university students, contain low level residues of toxic agrichemicals (herbicides, pesticides etc.) and chemicals (solvent hexane, benzene and derivatives, crude oil residue "non-volatiles" etc.) and biochemical substance (Bt toxins etc) cause organic damage lesions to their brains;

　　3)这些有毒农药、化学品、生化物质残留，在不同年龄不同状况人群造成不同的大脑功能障碍疾病与症状;

　　3) Toxic residues of these agrichemicals, chemicals, biochemicals, cause different brain dysfunctions in groups of people with different ages and different situations;

　　4)超低微量这些毒性农药、化学品、生化物质残留，单独或不同组合协同，造成细胞毒性、基因毒性、基因突变，造成人类中越来越多基因异常;

　　4) Ultra-low levels of toxic residues of these agrichemicals, chemicals, biochemicals, individual or different combinations synergiclly , cause cytotoxicity, genotoxicity, genetic mutations, cause more and more genetic abnormality in humans;

　　5)某些这些毒性农药、化学品、生化物质残留具有内分泌干扰剂特征，超低微量持续接触对胎儿、婴儿、幼童的发育造成巨大危害;

　　5) Some of these agrichemical, chemicals, biochemicals residues exhibit characteristics of endocrine disruptors, ultra-low exposure will cause substantial harm to the development of fetuses, infants, young children.

　　6)孕妇普遍持续食用这样的食品，这些有毒农药、毒性化学品、生化物质残留具有能力通过孕妇血液透过胎盘屏障进入胎儿体内，对胎儿的发育，特别胎儿大脑的发育，造成器质性损伤;

　　6) Pregnant woman popular continue consume such food, these toxic agrichemicals, chemicals, biochemical residues have ability through pregnant woman""""s blood penetrate placental barrier enter the body of fetus, cause organic damage to the development of fetus, especially the development of their brains;

　　7)新生儿出生后食用含这些有毒农药、化学品、生化物质残留的婴幼儿配方乳粉，在婴儿及其大脑成长发育最关键的阶段，继续对婴儿大脑造成器质性损伤病变。

　　7) Upon born, infants consume infant formula products containing such these toxic agrichemicals, chemicals, biochemical residues, during the most critical growing phases of the infant""""s brain, continue cause organic damage lesions to their brains.

　　中国帕金森病“发病率近20年增长20倍”, 据流行病学统计，中国目前约有170万患者。帕金森病可能跟大脑本身的器质性改变有关。动物实验证明，一些农药和除草剂残留物可能会引发帕金森病发病，而一些环境因素也可能是发病的诱因。帕金森病呈现低龄化趋势，“青少年型帕金森病”患者占据总人数的10%。

　　Parkinson disease incidence increased 20 times during recent 20 years, according to epidemiological estimations, there are about 1.7 million Parkinson patients in China. Occurring of Parkinson disease symptoms likely is related to Physical changes to the brain. Animal experiments have already proved, some pesticide and herbicide residues might cause Parkinson disease, some environmental factors also might be inducing factors to the disease. The ages of Parkinson disease shows a trend of becoming younger. "Youth and teenage type Parkinson disease" patients account to 10% of total number of Parkinson disease patients.

　　来自世界帕金森病协会的统计数字显示，全球帕金森病患者超过400万人，其中我国有170万患者。55岁以上的人群患病率达1%，75岁以上人群的患病率超过2.5%。

　　Statistics from the World Parkinson Disease Federation show, there is total 4 million Parkinson disease patients worldwide, in which include 1.7 million in China. The preva1ence of Parkinson disease patient over 55 years old is 1%, over 75 years exceeds 2.5%.

　　另据调查，近20年来，我国大城市患帕金森病的人数猛增。1986年，每10万人中有84个患者，而到2001年，每10万人中1130个患者，在农村这一比例更高。据估计，我国每年有近10万人成为新发的帕金森病患者。

　　According to survey, during recent 20 years (1985 - 2004), the number of Parkinson disease patient rapidly increased in major cities. In 1986 the preva1ence was 84 patients/10000 people, but by 2001 increased to 1130 patients/10000 people, this rate is even higher in rural areas. According to estimation, (by 2004) 10,000 new Parkinson disease patients occur each year in China.

　　新华网，专家提醒：帕金森病早发现早治疗早获益，2005-04-11

　　Xinhua Network, Specialist alert: Parkinson disease early discover and treatment brings early benefits, 2005-04-11

　　http://www.xinhuanet.com/chinanews/2005-04/11/content_4043275.htm

　　2007年4月11日，中华医学会神经专业秘书蒋雨平教授日前在上海举行的“世界帕金森病日”患者教育公益活动上表示，中国帕金森病的发病率在近20年内至少增长了20多倍，发病率提高可能与环境及食品因素有关。”

　　April 11, 2007, Prof. Jiang Yu-ping, Neurology, China Medical Society, at the "World Parkinson Disease Day" education campaign indicated, the Parkinson disease incidence increased 20 times during recent 20 years, the increase of incidence might be related to environment and food factors."

　　蒋雨平说，根据1986年统计数据，中国帕金森病发病率为0.047%，而根据上海2000年的统计，这个数据已达到了1.14%，最近全国范围内的统计数据则高达2%左右。... 上海市健康教育所提供的数据称，据流行病学统计，中国目前约有170万患者。”

　　Prof. Jiang Yu-ping said, according to statistics data of 1986, the incidence of Parkinson in China was 0.047%; by 2000, the incidence increased to about 2%. ... According to the data provided by the Shanghai Municipal Health Education Institute, according to epidemiological estimations, there are about 1.7 million Parkinson patients in China.

　　他表示，已经有动物实验证明，一些农药和除草剂残留物可能会引发帕金森病发病，而一些环境因素也可能是发病的诱因。

　　He indicated, animal experiments have already proved, some pesticide and herbicide residues might cause Parkinson disease, some environmental factors also might be inducing factors to the disease.

　　新华网，专家：中国帕金森病发病率近20年增长20倍，2007-04-12

　　Xinhua Network, Specialists, the Parkinson disease incidence increased 20 times during recent 20 years in China, 2007-04-12

　　http://health.sohu.com/20070412/n249373631.shtml

　　虽然帕金森病患者以老年人居多，但从近年来发病及就诊的患者年龄来看，正呈现低龄化趋势，“青少年型帕金森病”患者占据总人数的10%。... (湖南省脑科医院神经外科主任医师)黄红星说，该院收治过的帕金森病人中最年轻的是一位26岁的患者，患病时年仅14岁。而在广州，甚至有年仅6岁的患者被确诊。

　　Although most Parkinson patients are old age, but from ages of patients the disease starts and going to the hospital in recent years, the ages show a trend of becoming younger. "Youth and teenage type Parkinson disease" patients account to 10% of total number of Parkinson disease patients. ... (director doctor, Dept. Neurosurgery, Hunan Provincial Brain Hospital) Huang Hong-xing says, the youngest Parkinson patient they received was 26 years old, who started the disease when he was only 14 years old. There was even a 6 years old patient diagnosed Parkinson disease in Guangzhou.

　　中国新闻网，帕金森病趋向年轻化 尽早识别就诊成治疗关键，2014年04月09日

　　China News Network, Parkinson disease patients becoming younger, 2014-04-09

　　http://www.chinanews.com/jk/2014/04-09/6045106.shtml

　　遗憾的是，科学家对于帕金森病究竟为什么发生、如何发生、怎样预防均没有得到确切的答案。

　　Unfortunate, scientist do not have definite answer to why Parkinson disease occurs, how it occurs, how to prevent it.

　　通过临床流行病学调查发现，随着农药的普及，例如杀虫剂、除草剂的暴露，以及一些工业化学制剂的使用，导致在该环境下工作、生活的人患帕金森病风险增加。

　　Through clinical epidemiology investigation it is found, following spreading of agrichemicals, like exposed to pesticides, herbicides, and exposure to application of some industrial chemicals, lead to increased risk of Parkinson""""s disease to people working and living in such environment.

　　北京回龙观医院副院长庞宇认为，这些症状的出现可能跟大脑本身的器质性改变有关。

　　Pang Yu, deputy director, Beijing Huilongguan Hospital, considers, occurring of Parkinson disease symptoms likely is related to Physical changes to the brain.

　　中国科学报，世界帕金森日 帕金森病“阴霾”何时消散，2014-04-12

　　http://scitech.people.com.cn/n/2014/0412/c1007-24887779.html

　　老年痴呆症(又称阿尔茨海默病)，已经成中国为老年人的第四大杀手，目前患者总数约有600万，居世界首位，并正以每20年翻一番的速度递增;目前老年痴呆患者平均年龄55岁左右，比20年前提前10年，呈现明显的年轻化趋势。目前认为,老年痴呆症是由于慢性或进行性大脑结构的器质性损害引起的高级大脑功能障碍的一组症候群。美国科学家发现，滴滴涕或许会提高老年痴呆症的患病风险。

　　Alzheimer""""s disease, has become the No.4 killer to old age in China, the number of patients is about 6 million, ranking 1st position in the world, and increase at a rate of doubling every 20 years; The average age of Alzheimer""""s disease at present is about 55 years old in China, 10 years younger than the average age of patients 20 years ago, showing clear trend becoming younger. It is considers at present, a group of syndrome of advanced brain dysfunction caused by chronic or progressive brain structure physical damage. American scientists discovered, DDT might increase the risk of Alzheimer""""s disease.

　　据国际老年痴呆病协会公布的数据显示，我国老年痴呆症患者数量已达600多万，并正以每20年翻一番的速度递增。全球每7秒钟就有一个人被确诊为老年痴呆，而每四个人中就有一个中国人。老年痴呆已成为仅次于血管病、癌症和脑卒中的第四大杀手。

　　According to the data announced by International Alzheimer""""s Disease Association, China already has 6 million Alzheimer""""s disease patients, and increasing at a rate doubling every 20 years. Globally, every 7 seconds one more Alzheimer""""s disease patient is diagnosed, and every 4 patients includes one Chinese patient. Alzheimer""""s disease has become the No.4 killer of old age following cardiovascular disease, cancer, and stroke.

　　甘肃省心理卫生协会，研究显示：国人痴呆早了10年，2009-02-07

　　Gansu Provincial Mental Health Association, Studies show, Chinese Alzheimer""""s disease patients are ten years younger, 2009-02-07

　　http://www.gsws.gov.cn/html/7/62/6852.htm

　　从各大医院近年来接诊数据显示，50多岁就患痴呆症的人呈上升趋势。据国际老年痴呆症协会统计，目前老年痴呆患者平均年龄55岁左右，比20年前提前10年，呈现明显的年轻化趋势。

　　Patient receiving data from major hospitals show, the number of patients in their 50s diagnosed with Alzheimer""""s disease is increasing. According to statistics from International Alzheimer""""s Disease Association, average age about 55 of patients diagnosed with Alzheimer""""s disease, is 10 years younger than average age of diagnosed patients 20 years ago, showing obvious younger trend.

　　南京日报，老年痴呆发病年龄提前10年 空巢老人成重灾区，2012-09-20

　　Nanjing Daily, Age when Alzheimer""""s disease begins has advance 10 years, situation of old age families with no younger generation with them is most serious, 2012-09-20

　　http://www.njdaily.cn/2012/0920/233169.shtml

　　老年痴呆症又称阿尔茨海默病性痴呆,是一种进行性发展的致死性神经退行性疾病,是发生在老年期及老年前期的一种原发性退行性脑病。目前认为,老年痴呆症是由于慢性或进行性大脑结构的器质性损害引起的高级大脑功能障碍的一组症候群。

　　Alzheimer""""s disease is a kind of progressive development of fatal neurodegenerative diseases, is an old age and presenium primary degenerative brain disease. It is considers at present, a group of syndrome of advanced brain dysfunction caused by chronic or progressive brain structure physical damage.

　　李帆、黄玉玲(陕西省西安市第一医院)，老年痴呆症的现状分析及健康教育，当代医学，2012年22期

　　Li Fan, Huang Yu-ling (Xian Municipal No.1 Hospital), Analysis of current situation of Alzheimer""""s disease and health education, Contemporary Medicine, 2012(22)

　　http://d.wanfangdata.com.cn/Periodical/ddyx201222117

　　美国科学家发现，滴滴涕或许会提高老年痴呆症的患病风险。他们在专业期刊《美国医学会杂志·神经病学卷》上撰文指出，老年痴呆症患者血液中的滴滴涕分解物表明了这点。

　　American scientists discovered, DDT might increase the risk ofAlzheimer""""s disease. Their study published by academic journal American Medicine Society Journal - Neurology" points out, DDT decomposition detected in the blood of Alzheimer""""s disease patients indicates this.

　　新华网，农药DDT或可引发老年痴呆，2014-01-29

　　http://news.xinhuanet.com/cankao/2014-01/29/c_133082941.htm

　　据世界卫生组织统计，抑郁症已成为世界第四大疾患,在全世界的发病率约为11%，严重的患者中有15%会选择自杀来结束生命。上世纪80年代，全国流行病学调查显示，当时抑郁症患病率仅0.76%。据不完全统计，目前我国抑郁症发病率高达5%～6%,平均发病年龄已低至30岁左右。另据一项流行病学调查估算，中国抑郁焦虑患者已达9000万人，但接受相关药物治疗的患者只占不到10%。我国自杀和自杀未遂的人群中，抑郁症患者占50-70%。抑郁症并非单纯的心理问题，而是有一定生物学基础的器质性疾病。

　　According to WHO statistics, depression has become the world""""s 4th-largest disease, world population preva1ence is about 11%, 15% of severe patients will select suicide to terminate their life. During 80s of past century, nationwide epidemiology survey indicated, the preva1ence of depression then was only 0.76%. According to incomplete statistics, preva1ence rate of depression in China is already 5% - 6%, average age advanced to about 30 years. According to estimations by another epidemiology survey, China at present has about 90 million depression patients, but only less than 10% of these patients receive medicine treatment. Among suicide and suicide attempts, depression patients account to 50% - 70%. Depression is not a simple psychological problem, but rather is a biological based of organic disease.

　　据世界卫生组织统计，抑郁症已成为世界第四大疾患。到2020年可能成为仅次于心脏病的第二大疾病。保守估计，全世界共有3.5亿名抑郁症患者。抑郁症在全世界的发病率约为11%，严重的患者中有15%会选择自杀来结束生命，2/3的患者曾有过自杀的念头，每年因抑郁症自杀死亡的人数估计高达100万。

　　According to WHO statistics, depression has become the world""""s 4th-largest disease. By 2020 might become the 1st-largest disease, following behind heart disease. According to conservative estimation, worldwide there are 350 million depression patients, world preva1ence is about 11%, 15% of severe patients will select suicide to terminate their life, 2/3 patients had considered suicide, each year it is estimated that as much of 1 million suicides is due to depression.

　　在世界卫生组织的自杀率统计中，亚洲地区自杀率最高的是韩国。

　　Among WHO""""s suicide statistics, South Korea is the nation with highest suicide rate in Asia.

　　2012年韩国自杀总人数达到14160人，占死亡人数的28.1%，比2002年上升了10.2%。韩国2010年的一份社会调查显示，每10名韩国中学生中就有6名患有抑郁症或是曾有过自杀的念头。女学生患抑郁症的比例(44.3%)比男学生(34%)高。首尔地区学生患抑郁症的比例最高，达到40.5%。

　　In 2012, a total 14160 people suicide in South Korea, amounting to 28.1% of total number of deaths, 10.2% higher than 2002. A social survey of South Korea in 2010 showed, 6 middle school students among every 10 ten students suffers depression or once had thought of suicide. The rate of girl students with depression (44.3%) is higher than boys (34%). Depression rate of students in Soul area is the highest, reaching 40.5%.

　　2012年，欧洲抑郁症协会发起了一项调查，共有来自英国、德国、意大利、丹麦、土耳其、西班牙和法国共7000名成年在职者接受了调查。结果显示，平均每10人中就有2人患有抑郁症。英国登上榜首，抑郁症比率高达26%;意大利最低，为12%。抑郁症每年给英国经济造成86亿英镑的损失，其中包括抑郁症导致的旷工损失、治疗费用、失业救济额外支出等。

　　In 2012, the European Depression Association initiated a survey, a total of 7000 adults in U.K., Germany, Italy, Denmark, Turkey, Spain and France accepted the survey. Results showed, there are 2 depression patients among every 10 people. U.K. has the highest depression rate, 26%; Italy the lowest, 12%. Loss caused by depression to U.K. economy each year amounts to 8.6 billion Pounds, including loss of work, medical treatment costs, unemployment extra paid benefits.

　　新民周刊，抑郁症：全球第四大疾患，2014-07-30

　　Xinmin Weekly, Depression: Global 4th largest disease, 2014-07-30

　　http://www.xinminweekly.com.cn/News/Content/4150

　　暨南大学附属第一医院精神医学科和睡眠医学中心主任、家庭医生在线医学委员会专家潘集阳教授指出，抑郁症并非单纯的心理问题，而是有一定生物学基础的器质性疾病。有研究发现，抑郁症患者的大脑结构，包括海马体积会出现萎缩，但通过药物治疗，这种萎缩有可能被减缓或逆转。

　　Prof. Pan Ji-yang, director, Mental and Sleep Medicine Center, Jinan University, pointed out, depression is not a simple psychological problem, but rather is a biological based of organic disease. Studies have found, the brain structure of depression patients, including shrinkage of hippocampal volume, treated by drugs can slow or reverse such shrinkage.

　　羊城晚报，抑郁症：是器质病变与性格无关，2014-09-12

　　Yangcheng Evening News, Depression: Is organic disease, not related to character, 2014-09-12

　　http://www.ycwb.com/ePaper/ycwb/html/2014-09/12/content_538527.htm?div=-1

　　据不完全统计，目前我国抑郁症发病率高达5%～6%。另据一项流行病学调查估算，中国抑郁焦虑患者已达9000万人。

　　According to incomplete statistics, preva1ence rate of depression in China is already 5% - 6%. According to estimations by another epidemiology survey, China at present has about 90 million depression patients.

　　“我国自杀和自杀未遂的人群中，抑郁症患者占50-70%，但接受相关药物治疗的患者只占不到10%，量化评估和规范治疗尤为重要。”中南大学精神卫生研究所所长李凌江教授在近日举行的“辉瑞中枢神经峰会”上指出。

　　"Among suicide and suicide attempts population, depression patients account to 50% - 70%., but only less than 10% of these patients receive medicine treatment. Quantitative eva1uation and standardize treatment is especial important." Prof. Li Ling-jiang, director, Institute of Mental Health, Zhongnan University, pointed out at the recent " Pfizer central nerve summit".

　　人民网，我国抑郁症治疗率不足10%  规范治疗尤为重要，2015-03-17

　　People""""s Network, Less than 10% depression patients receive medicine treatment, 2015-03-17

　　http://health.people.com.cn/n/2015/0317/c14739-26707392.html

　　8月20日，在第8次全国心理卫生学术大会上，北京安定医院副院长王刚透露，抑郁症的平均发病年龄已低至30岁左右。近些年，网络上也不时爆出年轻抑郁症患者自杀的消息，不禁让人担心抑郁症是不是在年轻化。

　　Aug. 20, 2015, at the 8th national mental health academic conference, Wang Gang, deputy director, Beijing Anding Hospital, revealed, the average age of patients beginning with depression has advance to about 30 years old. During recent years, the internet has from time to time reported suicide cases of young depression patients, worrying people whether the age of depression patients is becoming younger.

　　市德安医院心理科主任王瑞文说，对抑郁症诊断放宽让抑郁症人群范围整体在扩大，年轻人数量也相应变多，平均年龄被拉低了。“早在上世纪80年代，全国流行病学调查显示，当时抑郁症患病率仅有0.76%。现在，世界卫生组织(WHO)对中国大陆地区的抑郁症患病率推测为7%-8%。”

　　Wang Rui-an, director, Dept. psychiatrist, Dean Hospital, the diagnose of depression is relaxing allowing the total size of depression patients expand, which accordingly includes more young people, bringing the average age down. "During the 80s of the past century, nationwide epidemiological survey showed, the preva1ence of depression at the time was only 0.76%. At present, the WHO estimates China""""s depression preva1ence as 7% - 8%."

　　光明网，抑郁症发病率30年上升10倍，2015-08-25

　　Guangming Network, Preva1ence of depression increased 10 times over 30 years, 2015-08-25

　　http://news.gmw.cn/newspaper/2015-08/25/content_108799310.htm

　　中国自闭症(也称孤独症)发病率正不断攀升，患者已超1000万，发病率约为1%;孤独症儿童发病率20年内升高了10倍, 0到14岁的儿童患病者达200余万。国际上，该病男女的发病率男女比例大约4:1。在我国，男女患病率的比例更为悬殊，约为6:1到9:1之间。

　　China""""s autism incidence is continue rising, exceeding 10 million patients at present, incidence rate about 1%;

　　China""""s children autism incidence has increased 10 times over the past 20 years， with over 2 million 0 - 14 years old children patients. International, the ratio of male/female autism patients is about 4:1. In China, this ratio is aobut 6:1 to 9:1.

　　儿童孤独症的病因复杂，近年来研究认为，孤独症与脑部生理结构有关，是多种因素导致的结果，与遗传因素、器质性因素以及环境因素等有关。

　　The cause of autism in children is complex, recent studies consider, autism is associated with brain physiology, is result of multiple factors, is related to genetic factors, organic factors and environment factors.

　　脑器质性病变：... 有研究发现, 患儿脑部体积比同龄正常儿童相对要大, 结构也存在一定的异常, 如脑白质相对较大, 而大脑皮质、海马回和丘脑体积相对较小, 浦肯野细胞部分性受损且有体积萎缩现象。

　　Organic brain lesions: ... Some studies found, brain volume of autism children are relatively larger than normal age-matched children, structure also contains certain abnormalities, like relative larger brain white matter, and relative smaller cerebral cortex, hippocampus and hypothalamus volume, Purkinje cell section is damaged and volume contracted.

　　神经生物学因素：在脑部CT、MRI、单光子发射计算机断层扫描 (SPECT) 辅助检查中，SPECT 异常检出率高，... 提示有脑干功能损伤的可能性。

　　Neurobiological factors: ... In the brain CT, MRI, SPECT examination, abnormal SPECT detection rate is high, suggesting possible damage of brainstem function.

　　庄海英，叶美荣(上海市奉贤区精神卫生中心)，儿童孤独症患者的心理社会干预， 2008年6月3卷6期

　　Zhuang Hai-ying, Ye Mei-rong (Shanghai Fengxian District Mental Health Center), Psychosocial intervention of children with autism, July 2008 Vol. 3(6)

　　http://journal.9med.net/qikan/article.php?id=436445

　　2001年，中国残疾人联合会对五省一市0-6岁的残疾儿童进行抽样调查，总样本量为6万个。经过数据整理，显示出全国自闭症儿童的发生率为千分之0.97，约有10.4万人。平均每500个儿童中就有一个是孤独症患者。

　　In 2001, the China Disabled Persons"""" Federation carried out sampling survey of total 60,000 disabled children 0 - 6 years old in 5 provinces and one city. Upon analysis of data, it showed that nationwide autism preva1ence was about 0.97/1000, total about 104,000 autism children. On average, there was 1 autism child among every 500 children.

　　李敬，关于自闭症儿童状况的调研报告，北京孤独症康复协会，2009-6-17

　　Li Jing, Investigation report about autism children (sections), Beijing Autism Recovery Association, 2009-6-17

　　http://www.guduzheng.net/2009/6/20908.html

　　2002年报道：儿童孤独症，也称“自闭症”，是一种较为严重的发育障碍性疾病。该病男女的发病率差异显著，男女比例大约是4:1。在我国，男女患病率的比例更为悬殊，约为6:1到9:1之间。

　　Report in 2002: Children autism is a rather serious developmental disorder disease. Significant difference exist in it""""s male/female incidence, globally about 4:1. But in China, the difference is more dramatic, about 6:1 to 9:1.

　　金洋网，热点话题 ：孤独症发病率上升，2002-07-25

　　Jinyang Network, Autism incidence increases, 2002-07-25

　　http://www.ycwb.com/gb/content/2002-07/25/content_395140.htm

　　沈阳(2005)：以每年300-400人的速度递增，发病率呈急剧上升趋势。

　　Shenyang (2005): Children with autism have increased at the rate of 300 –400 each year, indicating a trend of rapidly increasing!

　　沈阳日报，发病率呈急剧上升趋势 聚焦当今“儿童孤独症”，2005-10-20

　　Shenyang Daily, Trend of rapidly increasing focuses on today’s “Children’s autism”, 2005-10-20

　　http://news.sina.com.cn/c/2005-10-20/10107218716s.shtml

　　深圳(2007)：儿童孤独症的发病率高达0.132%，是全国0.025%的平均水平的5倍多。

　　Shenzhen (2007)：Autism preva1ence rate 1.32% for children, five folds of the national average rate 0.025%.

　　南方都市报，深圳儿童孤独症发病率为全国五倍，2007-12-21

　　Nanfang City Daily, Shenzhen children autism preva1ence rate is five fold of national level, 2007-12-21

　　http://news.sina.com.cn/c/2007-12-21/012913116221s.shtml

　　南京(2008年报道)：孤独症儿童发病率20年内升高了10倍。“专家表示，造成孤独症的根本原因目前还不清楚，而且尚无特效药物，当前主要的干预手段是早期教育。”

　　Nanjing (reported in 2008): Autism rate of children have increased to 10 times within 20 years. “Specialists indicate, the fundamental reason causing autism is still not so clear at present, and there is not special effective drugs, early education is the main means of interference.”

　　中国中医药报, 南京儿童孤独症发病率上升20年内升高10倍，2008-04-18

　　China Chinese Medicine Newpaper, Nanjing children’s autism rate increasing, increased 10 times within 20 years, 2008-04-18

　　http://www.chinanews.com/jk/ysbb/news/2008/04-18/1224952.shtml

　　《科技日报》2009年报道，中国目前至少有100万的孤独症儿童，发病率呈急剧上升趋势，个别地方孤独症发病率为1.5%，20年内升高了10倍。

　　Science Daily report in 2009, in China, there are now over 1 million children with autism, which is rapidly increasing, the autism rate in various areas has reached 1.5%, increased 10 times over 20 years!

　　科技日报，别让孤独症夺走他们的快乐童年，2009-08-11

　　Science Daily, Don’t let autism take away their joyful childhood, 2009-08-11

　　http://cautism.com/2009/8-11/09811820398814.html

　　上海(2010)：上海有八千多自闭症患者，孤独症儿童发病率0.6%

　　Shanghai (2010): Shanghai has over 8,000 autism patients, Children autism rate has reached 0.6%。

　　新民周刊，自闭症成儿童疾病之首 调查称发病率达千分之六，2010-08-25

　　(Shanghai) Xinmin Weekly, Autism becomes the No.1 children illness, survey said autism rate has reached 0.6%, 2010-08-25

　　http://news.sina.com.cn/h/sd/2010-08-25/112020972095.shtml

　　2004年，市残联与市卫生局在18个区县进行了0-6岁户籍残疾儿童抽样调查，总样本量3万人。其调查结果显示：我市2-6岁儿童孤独症发生率在千分之1.53，按这个比例计算，北京市户籍人口中的孤独症儿童约为3000名，而目前其发病率呈上升趋势。

　　In 2004, the Beijing Disabled Persons"""" Federation conducted sampling survey in 18 districts/counties of the municipality to 0 - 6 years old disabled children total 30,000. The results show: The preva1ence of autism children 2 - 6 years old is 1.53/1000. Calculated on the basis of this preva1ence, it is estimated that about 3000 autism children exist in Beijing""""s population, and this preva1ence shows trend of increase.

　　北京市残疾人联合会，北京市残联与北京大学第六医院

　　签署孤独症儿童康复项目合作协议，2010-10-11

　　Beijing Disabled Persons"""" Federation, Beijing Disabled Persons"""" Federation and Beijing University No.6 Hospital sign autism children recovery project cooperation agreement, 2010-10-11

　　http://www.bdpf.org.cn/zxpd/gzdt/c5703/content.html

　　在复旦大学附属儿科医院举行的 “2011孤独症研究国际合作发展论坛”获悉，…在我国，目前虽然仍缺乏大规模的人群资料，但根据世界卫生组织的估计，中国目前至少有100万的孤独症儿童。

　　Learnt at“2011 Autism Research International Cooperation Development Forum” held at the Attached Pediatric Hospital of the Fudan University, … in China, because still lack of large scale population survey data, but, according to estimation by the WHO China at present has at least over 1 million children with autism.

　　解放牛网，全球儿童孤独症发病率约1%，2011-11-04

　　Jiefang Niu Website, Title: Global children autism rate about 1%, 2011-11-04,

　　http://news.ifeng.com/gundong/detail_2011_11/04/10420231_0.shtml?t=1328876190406

　　长春(2011)：长春市0-6岁儿童的孤独症发病率为1.5%。

　　Changchun (2011): Autism preva1ence rate 1.5% for children age 2 – 6 years.

　　中国吉林网，长春孤独症儿童患病率呈上升趋势，2011年02月18日

　　China Jilin Website, Changchun autism children preva1ence show increase trend, 2011-02-18

　　http://www.chinajilin.com.cn/content/2011-02/18/content_2184003.htm

　　哈尔滨(2011)：近年来孤独症患病率明显上升，2-6岁儿童患病率为2.27‰.

　　Harbin (2011): Autism preva1ence rate apparent increase trend, 2.27% for children age 2 – 6 years.

　　哈尔滨新闻网，哈市儿童孤独症患病率上升 男女患病比例为7：1，2011-04-02

　　Harbin News Website, Harbin children autism rate increasing, ratio of autism between boys and girls is 7:1, 2011-04-02

　　http://www.jk396.com/xexl/2/942.html

　　2014年报道:近年，广州幼儿园孤独症的患病率高达1/133，其中男孩患病率高出女孩，有些孩子出生六个月就被诊断患病。

　　中国新闻网，广州幼儿园孤独症患病率高达1/133 男孩居多，2014-04-03

　　http://edu.ifeng.com/news/detail_2014_04/03/35424507_0.shtml

　　在我国，从上世纪末到本世纪以来，自闭症经历了由罕见病到流行病的转变。《中国自闭症儿童发展状况报告》引用2013年广州的一项流行病学调查发现，广州普通幼儿园自闭症患病率为1/133，而这个患病率调查没有包括散居儿童以及特殊教育机构，因此实际发病率估计更高。

　　In China, since end of last century until this century, autism has experienced transition from a rare disease to an epidemic. "The status report on development of Chinese children with autism" (Oct. 2014) quoted an epidemiological investigation conducted in 2013 in Guangzhou which found, the autism preva1ence in normal kindergartens in Guangzhou is 1/133, and this investigation did not include scattered residence children and special education institutions, thus estimation of the actual preva1ence is even higher.

　　在我国自闭症患病率和世界其他国家相似，约1%。以此推算，我国自闭症患者可能超过1000万， 0-14岁儿童患儿的数量可能超过200万 。

　　The preva1ence of autism in China is similar to other nations, about 1%. Estimation accordingly, the number of autism children in China might exceed 10 million, the number of autism children 0 - 14 years old might exceed 2 million.

　　由于自闭症是先天的具有生物学基础的神经发育障碍，其核心症状将伴随患者终生，对患者和家庭生活质量可能的破坏性必须引起社会方方面面的重视。

　　Since autism is neurodevelopmental disorders innate with biological basis, its core symptoms accompany the whole life of the patient.

　　新华网，我国首部自闭症行业报告发布，2014-10-20

　　Xinhua Network, China""""s first autism report announced, 2014-10-20

　　http://news.xinhuanet.com/gongyi/2014-10/20/c_127117822.htm

　　据美国疾病控制与预防中心统计，1975年，全美自闭症谱系障碍的发病率为1/5000;而截至2014年，发病率已升至1/68;自闭症造成的社会经济负担也逐年增长，截至2012年，在发病率为1/88的情况下，已达1370亿美元。

　　According to USA CDC statistics, in 1975, preva1ence of autism spectrum disorder was 1/5000; by 2014, the preva1ence increased to 1/68; the social economic burden accordingly also increased year by year, by 2012, when the preva1ence was 1/88, the burden was already USD137 billion.

　　中国新闻网，中国“自闭症”患者超千万 发病率逐年攀升，2015-04-02

　　China News Network, China""""s autism patients exceeds 10 million, incidence increasing year by year, 2015-04-02

　　http://news.sina.com.cn/o/2015-04-02/150431675271.shtml

　　课题名为《湖北省18至36个月儿童自闭症谱系障碍流行病学和早期症状及生物学标记》的研究结果，在省妇幼保健院出炉。该调查结果显示：我省18至36月儿童孤独症发病率为0.58%，其中男孩发病率高于女孩，男女比例为4.8:1。据统计，2014年我省3岁以下儿童为198.1万多人，据此发病率推算，3岁以下儿童自闭症患者约有1.1万多人。

　　The result of project titled "Hubei provincial 18 to 36 month children autism spectrum disorder epidemiology and early symptoms and biological markers", is announced by the provincial maternal and child health care. The result shows: The autism children preva1ence among 18 - 36 months is 0.58%, preva1ence between boys/girls is 4.8:1. Per statistics, there are 1.981 million children below 3 years old in our province, accordingly, it is estimated there is about over 11000 autism children below 3 years old in Hubei province.

　　湖北日报，我省3岁以下自闭症发病率0.58%，2015-03-31

　　Hubei Daily, Children autism preva1ence below 3 years old in Hubei province is 0.58%, 2015-03-31

　　http://news.xinhuanet.com/local/2015-03/31/c_127642776.htm